Synthetic hexapeptide

GHRP-2

Also catalogued as Pralmorelin, KP-102, Growth hormone-releasing peptide-2.

CAS number: 158861-67-7
Molecular formula: C45H55N9O6
Molecular weight: 817.96 g/mol
PubChem CID: —

Identity

CAS number: 158861-67-7
Molecular formula: C45H55N9O6
Molecular weight: 817.96 g/mol
Residues: 6

A six-residue sequence containing D-alanine, D-2-naphthylalanine, and D-phenylalanine with a C-terminal amide; a plain one-letter rendering cannot express the D-residues or the non-natural naphthylalanine.

What it is

GHRP-2 is a synthetic hexapeptide built from a mixture of natural and non-natural amino acids, including three D-configuration residues and 2-naphthylalanine, terminating in an amide. It carries the international non-proprietary name pralmorelin.

It belongs to the growth-hormone-releasing peptide series developed from the enkephalin-derived work of Bowers and colleagues, and is described in the literature as a ghrelin-receptor (GHS-R1a) agonist.

Regulatory status

GHRP-2 is not an approved drug in the United States. Pralmorelin has been registered in Japan as a diagnostic agent; the research material listed here is not that product.

Primary literature

Adis Editorial. Pralmorelin. Drugs in R&D 2004;5(4):236–239.
PMID 15230633

Citation titles are reproduced verbatim from the journal record. A citation documents the molecule's published identity and history; it is not a claim about the material sold here.

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